NMN Benefits: Science-Backed Advantages for Your Health

NMN Benefits: Science-Backed Advantages for Your Health

With growing awareness of its benefits, NMN is becoming a popular addition to anti-aging regimens.

We’ve created this article to be your most comprehensive resource on how NMN supplements benefit every area of your health — from brain function and body composition to muscle strength, heart health, and even the appearance of your skin, hair, and nails.

So whether you’re male, female, young, middle-age or elderly, you’ll discover the benefits of NMN supplements and how they can help you become a better, healthier version of yourself.

Let’s get started…

What Is NMN Exactly?

NMN (Nicotinamide Mononucleotide) is a molecule found in several foods including broccoli, cabbage, cucumber, avocado and edamame. The concentration of NMN in these foods is typically around 1mg per 100g.

In contrast, NMN supplements contain various dosage levels, ranging from 250mg to 1000mg per serving.

The recommended dosage of NMN for men and women is around 500mg per day.

NMN is also a precursor to NAD+, a coenzyme involved in numerous essential processes throughout the body.

Once consumed, NMN is distributed throughout the body, reaching tissues and organs. Interestingly, it has even been present in cells since embryonic development.

Benefits of NMN Supplements

Brain Health 

Several studies report that NMN may have positive effects on brain health, function and overall cognitive health in both animals and humans.

Research suggests that NMN may benefit older people by improving cerebromicrovascular endothelial function. This is particularly exciting considering the rise of brain diseases such as Dementia and Alzheimer's.

Can NMN protect your brain?

The research seems to indicate yes…

One study published on Cell.com revealed that NMN improved several neuronal brain functions including plasticity of synapses and overall cognitive performance. Another study revealed that NMN increases NAD+ levels in the brain, a molecule linked to improved mitochondrial function and reduced oxidative stress, two things associated with aging.

What about learning and memory?

Animal studies have indicated that NMN can help improve learning ability and memory.

Imagine mastering new job skills with ease, retaining information for longer, or picking up a new language faster. NMN supplementation could potentially support these goals by enhancing your learning ability and memory.

While NMN research is still in its early stages, the potential benefits for brain health are exciting, especially for those who prioritize continuous learning.


Best NMN Supplement

Weight Management

Struggling with weight management? Research on NMN is uncovering a promising link to weight loss, offering a potential new tool in your health journey.

We all know the dangers of excess weight – increased risk of diabetes, heart disease, and more. So, any safe and effective support system is worth exploring.

Early studies using NMN supplementation in animals have shown encouraging results. One such study found that mice given NMN experienced a decrease in body weight and fat mass, alongside improved insulin sensitivity.

But what about humans? 

Human trials are revealing similar promise. A study involving overweight and obese adults found that NMN supplementation led to reductions not only in body weight but also in BMI and waist circumference. Interestingly, these effects appeared to be more pronounced in women than men.

So, what's the science behind this potential benefit?

NMN might play a role in boosting cellular energy metabolism and expenditure, ultimately leading to weight loss.

Muscle Health

NMN’s effect on muscle health, strength and performance is interesting, especially for athletes or those seeking optimum physical conditioning.

Although losing muscle mass as we age is inevitable, NMN may help slow the loss and extend your physical prime.

Frontiers in Pharmacology published a study comparing the effects of exercise and NMN on muscle health in obese mice. Interestingly, NMN increased NAD+ levels in both muscles and the liver, while exercise alone only impacted muscle NAD+.

Furthermore, the study revealed that NMN improved two key factors for muscle health – glucose tolerance and insulin sensitivity.

Building on this promise, a Nature.com study showed that NMN elevated blood NAD+ levels in healthy older adults and positively influenced muscle function. Additionally, a Cell.com study demonstrated that NMN supplementation improved muscle function and even increased lifespan in mice.

Overall, the research suggests NMN may hold promise for muscle health, with potential benefits including improved muscle strength and performance, enhanced insulin sensitivity, and better glucose tolerance.

Cardiovascular Health

Our heart is arguably the most vital organ for a long and healthy life. Exciting new research suggests NMN may offer benefits for heart health.

One study explored how NMN stimulates glycolysis, the process cells use to break down glucose for energy. The research suggests NMN can improve overall heart function by increasing the production of ATP, a molecule that fuels cellular activity.

Improved Blood Vessel Health

NMN has a protective effect on blood vessels, potentially reducing oxidative stress, a major contributor to heart disease. Reduced oxidative stress means improved blood vessel function, lowering heart disease risk.

Enhanced Blood Flow

Another study found NMN can increase the production of nitric oxide, a molecule that helps blood vessels dilate for better overall flow. Improved blood flow contributes to better cardiovascular health and a reduced risk of heart disease.


NMN is gaining popularity as an anti-aging supplement, thanks to its ability to boost NAD+ levels in the body.

NAD+ is a critical molecule that declines with age and plays a vital role in numerous cellular processes, including DNA repair.

Anti-aging enthusiasts are exploring NMN supplementation as a method to enhance cellular health by supporting NAD+ production.

Early animal studies have shown exciting possibilities for NMN's anti-aging effects:

Enhanced Mitochondrial Function

NMN may improve how cells produce energy, boosting vitality.

Reduced Inflammation

NMN may lessen inflammation, preventing conditions like arthritis.

Increased Lifespan

NMN could contribute to a longer lifespan, although more investigation is needed.

The potential of NMN as an anti-aging tool is certainly intriguing. As research continues to develop, we'll gain a deeper understanding of how NMN may support longevity and overall well-being.

Diabetes Prevention

Insulin is a hormone that is produced by the pancreas and is responsible for regulating blood sugar levels.

Insulin sensitivity refers to the ability of cells to respond to insulin and take up glucose (sugar) from the blood.

In people with insulin resistance, cells become less responsive to insulin, leading to elevated blood sugar levels and an increased risk of type 2 diabetes.

A study published in Science found that NMN increased muscle insulin sensitivity in prediabetic women.

In the study, 10 women were given NMN supplements for six weeks.

The results showed that NMN increased skeletal muscle insulin signalling as well as insulin sensitivity and glucose uptake.

The same study also found that NMN increased the expression of genes involved in mitochondrial biogenesis and function.

This suggests that NMN may have potential as a therapeutic agent for people with insulin resistance or type 2 diabetes.

Energy Levels

In today's fast-paced world, a little extra energy can go a long way.

Enter mitochondria, the powerhouses within each cell that fuel our bodies.

NMN boosts NAD+ levels within these mitochondria, which, in turn, enhances their function and increases ATP production.

This means that supplementing with NMN may help to boost energy levels and combat fatigue.

In addition to its effects on mitochondrial function, NMN has also been shown to support processes involved in DNA repair.

This is important because DNA damage can impair energy metabolism, leading to reduced energy levels.

By promoting DNA repair, NMN may help to maintain optimal energy production in the body.

Eye Health

Since eyesight is one of our most critical faculties, prioritizing eye health is essential. NMN research suggests it may play a role in protecting our vision.

Through NMN’s ability to increase NAD+ levels, oxidative stress and inflammation can be reduced body-wide, including your eyes.

Beyond its broader effects, NMN also shows promise for directly benefiting eye health.

A study reported in Oxidative Medicine and Cellular Longevity revealed that NMN eliminates senescent (aged) cells in a human experiment on macular degeneration, an age-related eye disease. And in mice, NMN restored retina structure while simultaneously reducing senescence.

Hair Health

Luxurious, healthy hair is a timeless source of confidence, regardless of age. 

While the beauty industry offers countless solutions for thick, healthy locks, NMN is emerging as a credible supplement to improve hair health, texture, and shine. Here’s how:

Enhanced Blood Flow

One of the ways that NMN benefits hair health is by increasing blood flow to the scalp.

This increased blood flow can help to deliver nutrients and oxygen to the hair follicles, which can stimulate hair growth.

Reduced Inflammation

Additionally, NMN can help to reduce inflammation in the scalp, which can contribute to hair loss.

Keratin Production

NMN supports the production of keratin, a protein vital for hair strength, elasticity, color, and texture. This can lead to improved overall hair health and appearance.

Protection from Damage

NMN may help shield hair from environmental aggressors like pollution and UV radiation, which can cause dryness, brittleness, and breakage.

Skin Health

Younger-looking skin is what we all want but modern living seems to be working against us. This is where supplements like NMN can offer support.

As NAD+ levels decline with age, cell function weakens and damage increases. Research suggests NMN may help by boosting NAD+ levels, potentially leading to improved cellular function and reduced damage. 

This, in turn, translates to better skin health and texture.

Improved Texture

One study found that NMN increased collagen production and reduced wrinkles in mice.

Enhanced Elasticity and Hydration

Another study found that NMN supplementation increased skin elasticity and hydration in human subjects.

Potential Anti-Inflammatory Effects

Chronic inflammation contributes to skin aging and damage.

NMN may also have anti-inflammatory properties, which could benefit skin health.

Note: NMN should not be used as a replacement for proper skin care practices, such as wearing sunscreen and avoiding excessive exposure to UV radiation.

Sleep Quality

Getting a full night of deep sleep is the foundation for health and well-being.

NMN studies have revealed that NMN can improve sleep quality, reduce sleep disturbances, and increase sleep duration.

This is because NMN supports the production of NAD+, which is essential for regulating the body's circadian rhythm.

With a synchronized circadian rhythm, you’ll enjoy deep, restful sleep.

Disease Prevention

Studies suggest NMN may hold promise in reducing the risk of Alzheimer's disease and other neurodegenerative disorders. This protective effect stems from NMN's ability to support healthy mitochondrial function.

By promoting healthy mitochondria, NMN may have a cascading effect throughout the body, potentially helping to prevent a range of diseases.

In fact, a resilience-based lifestyle – one that incorporates a healthy diet, smart supplementation choices, and daily movement – can potentially ward off many negative health outcomes by strengthening the gut, immune system and circulatory system.

Aerobic Capacity

A study involving amateur runners explored NMN's potential for athletic performance.

Here, NMN supplementation significantly improved aerobic capacity compared to a placebo.

Furthermore, the study suggests NMN might be even more effective than exercise alone in promoting fat metabolism within the liver.

Combining NMN with a regular exercise routine may offer significant advantages for both blood sugar control and aerobic capacity.

NMN Supplement Benefits For Men

Men constantly strive for an advantage, whether in the gym, the boardroom, or simply feeling their best. 

Research suggests that NMN supplements might hold the key to unlocking a range of health benefits specific to men's needs.

Enhanced Physical Performance

One of the most exciting areas of NMN research for men is its potential to enhance physical performance. 

Studies indicate that NMN supplementation may improve aerobic capacity, endurance, and strength – all crucial factors for athletes and fitness enthusiasts. 

Notably, research suggests NMN could be particularly beneficial for older men experiencing a decline in physical function.

Boosted Testosterone Levels

Men seeking to optimize testosterone levels for muscle gain, strength, and even anti-aging benefits may find NMN research intriguing.

Testosterone, a crucial hormone produced in the testicles, plays a vital role in male development, including muscle mass and bone density. It also helps regulate red blood cell production and mood.

Studies suggest a potential link between NMN supplementation and increased testosterone levels.

One study involving male rats showed a significant increase in testosterone (up to 60%) compared to the control group when supplemented with NMN. Another study on aging male mice demonstrated that NMN not only increased testosterone levels but also improved muscle function.

Prioritizing Strength and Muscle Growth

Adequate testosterone levels are crucial for muscle development and strength gains. NMN's potential to elevate testosterone could be beneficial for gym-goers.

Mitigating Age-Related Decline

Testosterone levels naturally decrease with age. NMN supplementation might help mitigate this decline and support feelings of vitality and strength for longer.

NMN Supplement Benefits For Women

Many women prioritize healthy aging, hormonal balance, and maintaining a youthful appearance. Exciting research suggests NMN may offer a range of benefits specifically for women's health.

Enhanced Fertility Potential

Age-related decline in fertility is a common concern for women. Fortunately, research on mice shows promise for NMN's potential to improve female reproduction.

One study
suggests NMN may enhance the quality and quantity of eggs, leading to more successful fertilization. These findings offer hope for women seeking to optimize their fertility later in life.

Combating Age-Related Weight Gain

Another concern for women as they age is weight management.

This study showed that NMN significantly suppressed age-associated weight gain in mice after 12 months without showing any signs of toxicity.

This is a promising sign for counteracting one of the common processes of aging, being an increase in fat mass.

Boosting Energy and Physical Performance

Maintaining energy levels is essential for an active lifestyle. Research suggests NMN may benefit women's physical performance by improving energy metabolism.

Studies in mice have shown NMN can increase energy metabolism and physical activity levels, potentially by helping to prevent age-related decline.

For women committed to overall wellness, maintaining youthful vitality, and increasing energy levels – whether for daily activities or more ambitious goals – NMN may be a valuable addition to their longevity supplements.

Comprehensive Overview of NMN Benefits

Benefit Description
Brain Health Enhances cognitive function, improves learning and memory, and may protect against neurodegenerative diseases such as Alzheimer's.
Weight Loss Supports weight management by improving insulin sensitivity and reducing body weight and fat mass.
Muscle Health Improves muscle strength and performance, enhances insulin sensitivity, and supports glucose tolerance.
Heart Health Boosts heart function by increasing ATP production, improves blood vessel health, reduces oxidative stress, and enhances blood flow.
Anti-Aging Increases NAD+ levels, enhances mitochondrial function, reduces inflammation, and may extend lifespan.
Diabetes Prevention Improves insulin sensitivity, supports glucose uptake, and enhances mitochondrial function, potentially benefiting individuals with prediabetes or type 2 diabetes.
Energy Levels Boosts ATP production in mitochondria, supports DNA repair, and combats fatigue, leading to increased energy levels.
Eye Health Reduces oxidative stress and inflammation, protects against age-related eye diseases such as macular degeneration, and restores retina structure.
Hair Health Increases blood flow to the scalp, reduces inflammation, supports keratin production, and protects hair from environmental damage.
Skin Health Enhances collagen production, improves skin elasticity and hydration, and may reduce inflammation, promoting healthier and younger-looking skin.
Sleep Quality Improves sleep quality, reduces disturbances, and increases sleep duration by supporting circadian rhythm regulation.
Disease Prevention Supports mitochondrial health, which may help reduce the risk of diseases like Alzheimer's and other neurodegenerative disorders.
Aerobic Capacity Enhances athletic performance, improves aerobic capacity, and promotes fat metabolism
Men's Health Enhances physical performance, boosts testosterone levels, and improves muscle function, potentially benefiting strength and vitality.
Women's Health Enhances fertility potential, combats age-related weight gain, boosts energy levels, and improves physical performance.

Always consult a doctor before using NMN, especially if you have pre-existing health conditions or take medications.
NMN may cause side effects, so discussing the risks and benefits with your doctor is crucial for determining if NMN is right for you.

Wrapping Up

Looking for the best NMN supplement? Here are some key factors to consider:

  • Source Country and Manufacturing Standards: Choose an NMN supplement made in a country with strict quality controls, ideally in a GMP-certified facility.
  • Customer Reviews: Look for positive reviews from satisfied customers.
  • Purity Level: Opt for an NMN supplement with a high purity level.
  • Storage: Ensure the NMN is stored in tinted glass containers to protect against light and heat.

AlphaCell Labs offers NMN supplements that meet many of these criteria.

Our product boasts a 99% purity level and is manufactured in Australia, a country known for its high-quality standards.

We also prioritize customer satisfaction and offer free worldwide shipping to many countries.

For high-grade NMN capsules containing 99% purity, AlphaCell’s NMN checks all the boxes, and has the 5-star ratings to back it up. Click to find out more.

In addition, here on our website you’ll find plenty of NMN before and after photos and stories to give you confidence in choosing AlphaCell.